The state of Wyoming, in the heart of the country's Midwest region, is a paradox of sorts. While it ranks 10th in terms of total area, it is 50th when it comes to total population. According to the 2010 census the number of Wyoming residents numbered just under 564,000. To give you some perspective, New York City alone has a population 16 times larger than the entire state of Wyoming. Nonetheless, the experience of buying your first home is no different there than anywhere else in the country.